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Progress of pseudotumor cerebri (PC) due to use of lithium is observed very rarely and it is included in the literature as case reports. PC is defined as increase of intracranial pressure in the absence of a structural lesion such as intracranial space occupying lesion, meningeal inflammation or venous congestion. Its etiology and pathogenesis is not illuminated. In this paper 39 years old, bipolar disorder diagnosed male patient with developing PC after the addition of lithium to his treatment is presented. The patients complaints of headache, nausea, vomiting and double vision started at 10th day of usage of lithium and as a result of all the examinations of the patient PC were diagnosed. No reason can be detected that may cause the formation of the PC other than lithium. Disappearance of all clinical symptoms of the patient after cessation of lithium also supported the diagnosis. PC related to lithium cases in the literature, which are observed rarely with the case reports, are also reviewed. [Anadolu Psikiyatri Derg 2012; 13(1.000): 85-88]