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Objective: The aim of this research is to investigate the effectiveness of solution focused therapy which is based on interpersonal relationship theory in retrospective methodology. Methods: This research was planned as a pre/posttest without control group. The research population included 36 students who are registered a school of health of a university and applied to psychological consultation services of their school for their psychological issues. Students introduction and consulting form, Beck Anxiety Scale, Beck Depression Scale, Problem Solving Inventory were used as data collection forms. All ethic permission was provided. In this research, the five sessions solution focused therapy approach which is based on Peplaus interpersonal relationship theory was used for students. Inventories were applied both before and after the therapy sessions. Descriptive statistics, independent sample t test, Mann Whitney U test, Kruskall Wallis test were used for data analysis. Conclusion: When the scores of anxiety, depression and problem solving skills were compared before and after sessions; anxiety, depression and problem solving inventory. They were found that the mean scores of inventories decreased as statistically significant. Differences of scores when participating joyful activities and having someone which can be shared for their individual problems in depression was found decreased as statistically significant. Also it can be seen the some direction when having actively a kind of hobby in anxiety and problem solving skill scores differences. Discussion: It can be said that the five sessions solution focused therapy which is based on Peplaus interpersonal relationship therapy was affected for students which are applied psychological consultation services for their problems. [Anadolu Psikiyatri Derg 2016; 17(4.000): 261-269]