Objective: We aimed to evaluate the reliability and validity of a Turkish adaptation of the Premenstrual Symptoms Impact Survey (PMSIS), a six-question health survey that measures the impact of symptoms of premenstrual syndrome (PMS) on an individuals functional health and well-being. Methods: The PMSIS was independently translated into Turkish and its adaptation to Turkish language was performed via back-translation. The reliability and validity of the PMSIS were examined with 63 women of reproductive age, found healthy during annual well-woman gynecologic examination. Premenstrual Syndrome Scale (PMSS), a Turkish questionnaire, was administered to assess the concurrent validity of the PMSIS. For the assessment of survey data, the content validity, test-retest reliability, Cronbachs alpha, concurrent validity, and construct validity tests were used. Results: The content validity index of the Turkish version of PMSIS was found as high (91%). After reliability analyses, the intra-class correlation coefficient between the PMSIS scores at the first and second assessments was 0.70, showing a good agreement between test and retest values; and the Cronbachs alpha coefficient was 0.89, indicating adequate and high internal consistency. Regarding the concurrent validity, the Pearson's correlation coefficient between the PMSIS (first assessment) and PMSS scores was 0.70 (p=0.001). Regarding the construct validity, factor analysis revealed that one dimension was found; and factor loading of items ranged from 0.74 t0 0.84 and total variant of scale was expressed as 65.1%. The PMSIS had a good concurrent and construct validities. Conclusions: The Turkish version of PMSIS has good reliability and validity properties. It is a reliable, consistent, and valid instrument to assess the status of PMS in women of reproductive age and the outcome of PMS treatment in Turkish population. [Anadolu Psikiyatri Derg 2015; 16(3.000): 205-211]