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Objective: The families, when faced with difficult life events, use a specific key processes of resilience. The main objective of this study was to determine the predictor role of family resources and stressful events through which the family passes in relation to the advancement of drug users through the process of change (termination of abuse) and in relation to the quality of life of the addict. Methods: To obtain data subjects were surveyed through four questionnaires. The questionnaire with general information, FILE scale gives the index of family stress, and family vulnerability as a result of the aggregation of life events experienced by families. FIRM is the scale used for social support, WHODAS generic instrument for assessing health and disability, including mental, neurological and addiction. URICA was used for testing stages of change. The sample consisted of 200 patients who were hospitalized at the department of addiction. Results: Our study confirmed that there is a significant correlation between family resources and life events. Correlation between quality of life and life events is not statistically significant at the total score of quality of life, nor individual domains. Only in the area of quality of life relating to cognition, there is a weak negative correlation. Conclusion: Family resources and stressful life events do not affect the quality of life in the process of change but there is a significant correlation between family resources and stressful life events and families that have passed through periods of life events can strengthen their individual capacities. [Anadolu Psikiyatri Derg 2016; 17(4.000): 278-284]