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Objective: This randomized-controlled experimental study was conducted to determine the effects of psychoeducation in the clinic and regular telepsychiatric follow-up (via telephone) after discharge on social functioning, drug adherence of patients with schizophrenia. Methods: This study was performed on totally 62 patients, assigned to experiment (n=32) and control (n=30) groups, from 1st July 2010 to 31st May 2011, being followed in Mental Health Center of Kayseri Training and Research Hospital and meeting research criteria. Patients characteristics were recorded by a form. For the patients in experiment and control groups; before education, after education and after 6-months telephone follow-up Scales of Medication Adherence Rating, Social Functioning were applied. In the psychoeducation process, the patients in the experiment group were given Manual of Information for Patients with Schizophrenia prepared by the researcher. After discharge, patients were interviewed by telephone for 6 months, every week regularly in average for 15 minutes. A standard, semi-structured interview form consisting of 7 questions were used for telephone follow-up. Results: For the patients in the experiment group, after psychoeducation and telephone follow-up, the mean scores for adherence to treatment and social functioning scores were increased, the differences between before and after education and after telephone follow-up were significant. Again, the differences between the mean scores of adherence to treatment and social functioning were significant after education and after telephone follow-up for the patients in both experiment and control groups (p [Anadolu Psikiyatri Derg 2013; 14(3.000): 192-199]