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Objective: This research was conducted to define the relationship of childhood trauma and aggression in bipolar disorder. Methods: This study was conducted between December 2015 and March 2016 in Manisa Mental Health Diseases Hospital. The study population consisted of 449 patients. The minimum sample size of the universe is calculated 209 with 95% confidence interval and 5% standard deviation using the known formula. The data, is collected using Information Form, Childhood Trauma Questionnaire (CTQ-28), Buss-Durkee, and the Aggression Scale. The data was evaluated by number, percentage, t test, one-way analysis of variance, Mann-Whitney, Kruskal-Wallis and the Pearsons correlation coefficient in SPSS 22.0 program. Results: The average age of the patients is 34.71±11.16 (range: 18-65). 61.7% of the patients are male, 50.2% of patients are single, 34.0% of patients are primary school graduates. Income status of patients; 48.8% of patients the income is less than expenses. Sociodemographic characteristics such as the income situation of the patient, marital status, education level, parents' education, place of residence, immigration status, self-harm state with childhood trauma scale total score and Buss-Durkee Aggression Scale was found a statistically significant correlation between subdomains. Conclusion: Our results are suggest that there can a relationship between childhood trauma and aggression levels in bipolar disorder. [Anadolu Psikiyatri Derg 2018; 19(2.000): 163-168]