The discovery of corticosteroids in 1949, revolutionized the practise of medicine. Corticosteroids become the mainstay of therapy for a variety of acute and chronic diseases (e.g., endocrinopathies, cancer, inflammatory diseases, systemical lupus erythematosus, multiple sklerosis, and asthma). Corticosteroids often induce psychiatric syndromes, including depression, mania, psychosis, delirium, obsessive-compulsive symptoms, suicidality, cata-tonia and reversible dementia. In our case, we will discuss 67 years old male patient who developed psychotic disorder after receiving systemic corticosteroid treatment. [Anadolu Psikiyatri Derg 2016; 17(1.000): 74-76]