ALPHA PSYCHIATRY
Invited Review

Neuropsychiatric Consequences of COVID-19 Pandemic: A Synthetic Review from a Global Perspective

1.

Somnogen Canada Inc., College Street, Toronto, Canada

2.

Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India

3.

Sleep research unit, Department of Psychiatry, Faculty of Medicine, Mansoura University, Egypt

4.

Department of Psychiatry, North Area Armed Forces Hospital (NAAFH) KSA, Saudi Arabia

5.

Department of Rehabilitation Medicine, North Area -Armed Forces Hospital (NAAFH)-KSA, Saudi Arabia

6.

Department of Chest Medicine, Faculty of Medicine, Mansoura University, Egypt

7.

Department of Nursing, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia

8.

University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia

9.

Strategic Technologies Program of the National Plan for Sciences and Technology and Innovation in the Kingdom of Saudi Arabia

10.

College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Kingdom of Bahrain

11.

Ministry of Health, Manama, Kingdom of Bahrain

12.

Division of Community Psychiatry, M. S. Chellamuthu Trust and Research Foundation, Madurai, India

13.

Independent Researcher, Narayanapuram, Madurai, Tamil Nadu, India

14.

Department of Psychiatry, Chulalongkorn University Faculty of Medicine, Bangkok, Thailand

15.

Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

16.

Department of Medicine, Columbia University, New York, NY, USA

17.

Department of Psychiatry, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India

18.

Department of Neuropsychiatry and Behavioral Science, Columbia, University of South Carolina, South Carolina, USA

19.

Department of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland

20.

Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, Texas USA

21.

The Institute for Mental and Physical Health and Clinical Translation Strategy Research Centre, Deakin University School of Medicine, Geelong Victoria, Australia

22.

School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

23.

Department of Psychiatry, University of Melbourne, Parkville, Australia

24.

Orygen Youth Health Research Centre, Parkville, Australia

25.

Department of Psychiatry, University of Toronto, Canada

26.

SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, South Africa

27.

Neuroscience Education Institute, University of California San Diego, San Diego, CA, USA

28.

Departments of Psychiatry, Neuroscience, and Pharmacological Sciences, Mount Sinai School of Medicine, New York, NY, USA

Alpha Psychiatry 2022; 23: 144-154
DOI: 10.5152/alphapsychiatry.2022.21783
Read: 24 Downloads: 30 Published: 17 February 2022

Some research suggests that distress, secondary to isolation and fear following COVID-19 infection, can negatively affect the long-term more than the COVID-19 infec- tion itself. This narrative review aims to provide a global view on the neuropsychiatric con- sequences of COVID-19 that can be ascribed to several factors, ranging from the direct effect of infection, to the body’s responses against the infection, or to the psychologi- cal sequelae of social isolation, unemployment, and fear for one’s health and livelihood. Current findings show that the more severe the respiratory infection, the more likely are central nervous system (CNS) complications regarding the infection itself. The immune reactions to the infection may result in symptoms similar to chronic fatigue as well as neurocognitive deficits, which last long after the infection is gone. An increase in symp- toms of depression, anxiety, and trauma-related stress may also follow upon economic fears and isolation from friends and family. The consequences of the pandemic are not limited to adults; children learning remotely and away from classmates and routine activi- ties may develop adjustment disorders, acute stress disorder, and a variety of manifesta- tions of grief. A summary of case reports suggests that COVID-19-related stress, economic recession, and political unrest increase the risk of suicidal behaviors and acts of violence. However, it is unknown whether manifestations of mental disorders result from social causes or whether CNS complications may be responsible.

Cite this article as: Pandi-Perumal SR, Zaki NF, Qasim M, et al. Neuropsychiatric consequences of COVID-19 pandemic: A synthetic review from a global perspective. Alpha Psychiatry. 2022;23(4):144-154.

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