Deep brain stimulation (DBS) of subthalamic nucleus is an effective treatment method for palliating Parkinsons disease. But this treatment has some psychiatric side effects. Mania, depression, suicide attempt and cognitive problems can be seen as side effects of deep brain stimulation. The mechanism of emerging these side effects is not well understood. In this article, in order to attract attention to multidisciplinary approach of DBS application in Parkinsons disease treatment, it is discussed that clinic and treatment of mania developed after DBS treatment of a Parkinsons disease patient who is 73 years old and has not any psychiatric disease in the past. [Anadolu Psikiyatri Derg 2016; 17(0.300): 64-67]