ALPHA PSYCHIATRY
Original Articles

Is there a relationship between basophil, platelet-related parameters and developmental stuttering?

1.

Antalya Egitim Ve Arastirma Hastanesi, Antalya, Turkiye

2.

Kahta Devlet Hastanesi

3.

Adiyaman niversitesi Egitim Ve Arastirma Hastanesi Psikiyatri Servisi, Zemin Kat

Alpha Psychiatry 2020; 21: 187-194
DOI: 10.5455/apd.57722
Read: 994 Downloads: 581 Published: 01 April 2020

Objective: Studies show that developmental stuttering (DS) may be associated with inflammatory processes. Complete blood count (CBC) values have been used as indicators of a systemic inflammatory response. We aimed to evaluate the relationship between CBC values particularly basophil, platelet, and lymphocyte-related parameters and DS. Method: In this retrospective case-control study, the CBC values of 54 patients who were diagnosed with DS were compared with the data of 54 healthy subjects. Results: Basophil count, percentage of basophil, and platelet count were significantly higher (p=0.001, r=0.35; p=0.044, r=0.19; p=0.045, r=0.11; respectively); mean platelet volume was significantly lower in the patient group (p=0.000, r=-0.54). The areas under the ROC curve of basophil count, percentage of basophil, and platelet count for patient group were 0.708, 0.611, and 0.636. A signifi-cant correlation was found between basophil count and platelet count (r=0.276, p=0.048), basophil count and mean platelet volume (r=-0.420, p=0.002), basophil count and percentage of basophil (r=0.685, p=0.000). Basophil count correlated with disease duration (r=-0.296, p=0.035). According to the Binary logistic regression analysis, low mean platelet volume predicts DS. Discussion: Inflammation might play a role in the etiopathogenesis of DS. Basophil and platelet-related parameters may be potential markers for DS. [Anadolu Psikiyatri Derg 2020; 21(2.000): 187-194]

Files
EISSN 2757-8038