ALPHA PSYCHIATRY
Original Articles

Impact of parental consanguinity on clinical features in schizophrenia

1.

Dokuz Eylul Universitesi Tip Fakultesi Ruh Sagligi ve Hastaliklari Anabilim Dali, Izmir, Turkiye

2.

Katip Celebi Universitesi Ataturk Egitim ve Arastirma Hastanesi Psikiyatri Bolumu, Izmir, Turkiye

3.

Dokuz Eylul Universitesi Tip Fakultesi Ruh Sagligi ve Hastaliklari Anabilim Dali, Izmir, Turkiye

Alpha Psychiatry 2017; 18: 22-28
DOI: 10.5455/apd.220350
Read: 525 Downloads: 267 Published: 01 February 2017

Objective: The purpose of this study was to evaluate the impact of parental consanguinity on the clinical features in schizophrenia. Methods: The sample of the study was based on DSM-IV schizophrenia patients admitted to Sinop Ataturk State Hospital between 2009 and 2001. Sociodemographic (age, gender, marital status, completed years of education, employment status) and clinical features (family history of psychiatric disorders, age of onset, number of hospitalization), and parental consanguinity were retrieved retrospectively from case registries. Results: A total of 182 patients (51.1% female and mean age 38.8 years) were included. Frequency of any parental consanguinity and first degree cousin marriages were 19.9% and 13.2% respectively. Mean age of onset of schizophrenia was significantly lower among patients with parental consanguinity than patients with no parental consanguinity (22.1 and 25.5 years respectively; t180=2.1, p [Anadolu Psikiyatri Derg 2017; 18(1.000): 22-28]

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