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Objective: We aimed to evaluate the effects of positive psychological intervention on Parkinson's disease (PD) patients complicated with depression and cognitive dysfunction. Methods: Two hundred and thirty-two PD patients complicated with depression and cognitive dysfunction treated in our hospital were selected and randomly divided into two groups (n=116). The control group was treated routinely and the observation group was additionally sub-jected to positive psychological intervention for eight consecutive weeks. They were evaluated by the Hamilton Depression Rating Scale (HAMD) and the Montreal Cognitive Assessment Scale in terms of depression and cogni-tive dysfunction. The numerical data between groups were compared by the χ2 test, and the categorical data were compared by the t test. Changes in the depression and cognitive function scores before and after intervention were compared by analysis of variance for repeated measures. P [Anadolu Psikiyatri Derg 2019; 20(4.000): 412-417]