ALPHA PSYCHIATRY
Original Articles

A common possible genetic etiology in trichotillomania and posttraumatic stress disorder comorbidity: a case report

1.

Bakirkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Disease Hospital

2.

Bakirkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Disease Hospital

3.

Istanbul Arnavutkoy State Hospital

4.

Just retired from Bakirkoy Prof. Dr. Mazhar Osman Mental Health and Neurological Disease Hospital

Alpha Psychiatry 2019; 20: 110-112
DOI: 10.5455/apd.302189
Read: 596 Downloads: 368 Published: 01 February 2019

Trichotillomania (TTM) is a psychiatric disorder can be triggered by traumatic events characterized by recurrent hair pulling. The incidence of post-traumatic stress disorder (PTSD) in TTM patients was also significantly higher than in the normal population. It is estimated that serotonergic system, dopaminergic system, hypothalamic-pituitary-adrenal (HPA) axis genes may be related with PTSD and TTM co-occurrence. When the literature is reviewed it is seen that serotonergic system gene especially 5HT-2A gene polymorphism may play an important role as a com-mon possible genetic background in the etiology of posttraumatic stress disorder and trichotillomania. It was also observed that effective results were obtained when agents acting on 5HT-2A receptor were preferred in the treatment. Here, we report a 20-year-old male patient who was diagnosed with TTM and PTSD as a result of trau-matic life event a year ago and we also aimed to discuss a possible common genetic etiology which may cause this comorbidity. [Anadolu Psikiyatri Derg 2019; 20(1.000): 110-112]

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